Serveur d'exploration sur le lymphœdème

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Setaria digitata in advancing our knowledge of human lymphatic filariasis.

Identifieur interne : 000B21 ( Main/Exploration ); précédent : 000B20; suivant : 000B22

Setaria digitata in advancing our knowledge of human lymphatic filariasis.

Auteurs : A N I. Perumal [Sri Lanka] ; Y I N S. Gunawardene [Sri Lanka] ; R S Dassanayake [Sri Lanka]

Source :

RBID : pubmed:25924635

Descripteurs français

English descriptors

Abstract

Setaria digitata is a filarial parasite that causes fatal cerebrospinal nematodiasis in goats, sheep and horses, resulting in substantial economic losses in animal husbandry in the tropics. Due to its close resemblance to Wuchereria bancrofti, this nematode is also frequently used as a model organism to study human lymphatic filariasis. This review highlights numerous insights into the morphological, histological, biochemical, immunological and genetic aspects of S. digitata that have broadened our understanding towards the control and eradication of filarial diseases.

DOI: 10.1017/S0022149X15000309
PubMed: 25924635


Affiliations:


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<div type="abstract" xml:lang="en">Setaria digitata is a filarial parasite that causes fatal cerebrospinal nematodiasis in goats, sheep and horses, resulting in substantial economic losses in animal husbandry in the tropics. Due to its close resemblance to Wuchereria bancrofti, this nematode is also frequently used as a model organism to study human lymphatic filariasis. This review highlights numerous insights into the morphological, histological, biochemical, immunological and genetic aspects of S. digitata that have broadened our understanding towards the control and eradication of filarial diseases.</div>
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